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为了探讨口服有机磷农药中毒后保留胃管重复洗胃对血胆碱酯酶活性的影响。将 180例口服有机磷农药中毒病人随机分为观察组和对照组 ,观察组 96例 ,保留胃管重复洗胃 ;对照组 84例 ,按常规法洗胃。观察两组每2 4h血胆碱酯酶活性变化。结果 :轻度中毒时 ,两组血胆碱酯酶活性比较 ,差异无显著性 (P>0 .0 5 ) ;中、重度中毒时 ,观察组血胆碱酯酶活性下降幅度小、回升快 ,与对照组比较 ,差异有极显著性 (P<0 .0 1)。提示保留胃管重复洗胃可将体内残留农药排出体外 ,血胆碱酯酶在无残毒继续抑制的情况下可迅速恢复活性。
In order to investigate the effects of repeated gastric lavage of gastric lavage on the blood cholinesterase activity after oral organophosphorus pesticide poisoning. 180 cases of oral organophosphorus pesticide poisoning were randomly divided into observation group and control group, 96 cases in observation group, keeping gastric tube repeat gastric lavage; control group, 84 cases, routine lavage. The change of blood cholinesterase activity was observed every 2 4 hours in both groups. Results: When mild poisoning, there was no significant difference in the blood cholinesterase activity between the two groups (P> 0.05). In moderate and severe poisoning, the decrease of blood cholinesterase activity in the observation group was small and rebounded rapidly , Compared with the control group, the difference was significant (P <0.01). Prompt to retain gastric tube repeat gastric lavage can be left in the body of residual pesticides, blood cholinesterase in the case of continued inhibition of residual toxicity can quickly restore activity.