论文部分内容阅读
目的提高原发性输尿管移行细胞癌的诊断水平和治疗效果.方法回顾性分析19例原发性输尿管移行细胞癌的临床特点、诊断、治疗及预后.结果19例随访1.5~8年.死亡7例,其中包括再发膀胱癌转移4例.再发膀胱癌发生率21.1%.5年生存率73.1%.结论结合多种检查手段可提高其术前确诊率.患侧肾输尿管全切及膀胱袖状切除术是首选术式.肿瘤分级、分期是决定预后的主要因素,分期更为重要.术后再发膀胱癌是输尿管癌预后不良的标志.术后抗癌药物膀胱灌注化疗可以降低膀胱再发癌的发生率,术后辅助全身化疗可能有助于改善输尿管浸润性尿路上皮癌的预后.“,”Objective: To improve the diagnosis and treatment of primary ureteral carcinomaMethods: Data of 19 cases of primary ureteral carcinoma were reviewed to evaluate the clinical characteristics, various kinds of diagnostic means ,and the prognosis . summarized the diagnostic and therapeutic experience. Results: 19 patients were folowed up for one and eight year.7 were dead, Among them, 4 died of recurrece of bladder cancer. Recurrence rate of bladder cancer was 21.1% .5year survival rate was 73.1%.Conclusion: The diagnostic accuracy of primary ureteral carcinoma might be improved by combined use of various kinds of the diagnostic means before open surgery. Nephroureterectomy and bladde cuff resection is the best treatment of primary carcinoma of Ureter.The prognosis mainly depend on the stage and pathology grade of the carcinoma.the clinical stage is more inportant. The postoperative recurrence of bladder cancer is a poor prognostic sign of ureteral carcinoma. Postoperative bladder perfusion chemotherapy may reduce Recurrence rate of bladder cancer. Postoperative adjuvant systemic chemotherapy may help to improve the prognosis of invasive urothelial carcinoma of ureter.