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目的:观察一贯煎联合小剂量奥曲肽治疗肝肾阴虚型肝硬化顽固性腹水的疗效。方法:将我院内科住院部收治的60例诊断为肝肾阴虚型肝硬化顽固性腹水的患者,随机分为治疗组和对照组,对照组采用小剂量奥曲肽和常规治疗。治疗组在对照组治疗的基础上加用一贯煎治疗。结果:治疗2个疗程后,治疗组的临床疗效总有效率为93.3%,对照组为70.0%,两组比较,差异有统计学意义(P<0.05);且经过治疗后,两组在腹围、体重和门静脉主干内径下降程度及24 h尿量增加程度等数据方面比较,治疗组明显优于对照组,差异有统计学意义(P<0.05)。结论:一贯煎联合小剂量奥曲肽治疗肝硬化顽固性腹水临床疗效较好,可明显改善临床症状及体征,使腹水消退迅速。
Objective: To observe the efficacy of decoction combined with low-dose octreotide in the treatment of refractory cirrhosis and liver cirrhosis with ascites. Methods: Sixty patients diagnosed as liver cirrhosis and liver cirrhosis with refractory ascites were randomly divided into treatment group and control group. The control group received low-dose octreotide and conventional treatment. The treatment group in the control group based on the treatment plus consistent fried treatment. Results: After two courses of treatment, the total effective rate of the treatment group was 93.3% and that of the control group was 70.0%. There was significant difference between the two groups (P <0.05). After treatment, Circumference, body weight and the diameter of the main portal vein and 24-hour urine output increased, the treatment group was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion: The combination of decoction combined with low dose of octreotide in the treatment of refractory ascites due to liver cirrhosis has better curative effect, which can obviously improve the clinical symptoms and signs and make the ascites subside rapidly.