论文部分内容阅读
本文报道三种肿瘤产生的淀粉酶的有关酶活性的特异性、相应的分子质量、等电点、抗原性以及氨基酸组成等特性;并与纯化的人唾液和胰淀粉酶作了比较。产生淀粉酶的肿瘤有(来自手术或尸检):肺支气管肺泡腺癌(例1,74岁,男)、上皮型胸腺瘤(例2,46岁,女)和严重乳头卵巢囊腺癌(例3,51岁,女)。淀粉酶活性采用Ceska等兰色淀粉法测定。例1和例2的淀粉酶活性为正常人的10~40倍。将无高淀粉酶血症的正常肺、卵巢组织中淀粉酶活性与肿瘤病例比较,正常肺、卵巢组织大多小于1U/
This paper reports the specificity of the enzymatic activity of the three types of tumor-derived amylase, the corresponding molecular mass, isoelectric point, antigenicity, and amino acid composition, and compares it with purified human saliva and amylase. Tumors producing amylase (from surgery or autopsy): lung bronchoalveolar adenocarcinoma (case 1, 74 years old, male), epithelial thymoma (case 2, 46 years old, female), and severe papillary ovarian cystadenocarcinoma (cases) 3, 51 years old, female). Amylase activity was measured using the Ceska et al blue color method. The amylase activity of Examples 1 and 2 was 10 to 40 times that of normal humans. The amylase activity in normal lung and ovarian tissues without hyperamyemiaemia was compared with tumor cases. Normal lung and ovarian tissues were mostly less than 1 U/