肌无力综合征即Eaton-Lambert综合征首先于1953年由Anderson等报道肺部肿瘤伴发有肌无力,随后其他作者相继报道了各自所见到的这种少见并发症。不久,Henson等及Heathfield等分别指出这类病例是一种非典型的重症肌无力。至1956年Eaton及Lambert等分析研究文献上所报道的30例这类肌无力的临床和生理特征指出这是一种完全不同于重症肌无力的肌无力综合征(Myasthenic Syndrome)。它多伴发于小细胞未分化肺癌,而且有些病例确定有神经 Myasthenia syndrome, known as Eaton-Lambert syndrome, was first reported in 1953 by Anderson et al., In which lung tumors were associated with myasthenia gravis. Other authors subsequently reported their rare complication. Soon, Henson et al. And Heathfield et al. Pointed out that this type of case is an atypical myasthenia gravis. The clinical and physiological characteristics of 30 cases of muscle weakness reported to Eaton and Lambert et al. In 1956 indicated that this is a Myasthenic Syndrome that is completely different from myasthenia gravis. It often associated with small cell undifferentiated lung cancer, and in some cases identified nerves