应激性溃疡在重症患者中有较高的发病率和死亡率,胃酸中和是一有效的预防措施。本文旨在比较ICU患者使用硫酸蔗糖(Sucralfate)与H_2受体拮抗剂加抗酸剂预防应激性溃疡的效果。 98例年龄>18岁,入院时置胃管和气管内插管至少需72小时的ICU的重危病人,随机分成两组,在年龄、性别、入院APACHE_Ⅱ评分、受伤严重度评分、校正创伤评分和吸烟史方 Stress ulcer in critically ill patients have a higher morbidity and mortality, gastric acid is an effective preventive measure. This article aims to compare the effects of Sucralfate and H 2 receptor antagonists plus antacids in the prevention of stress ulcer in ICU patients. Ninety-eight critically ill patients aged 18 years and admitted to the hospital with gastric and endotracheal intubation for at least 72 hours were randomly divided into two groups according to age, gender, admission APACHE II score, severity of injury score, And smoking history