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流行性病学资料表明,肺癌在我国的发病率呈上行趋势,其中癌性肺不张高达60.5％～80％,常规疗法多采取全身化疗、局部放疗等,疗效很不满意,且副作用较大。我院经过两年多的努力,在纤维支气管镜(以下简称纤支镜)直视下向瘤体组织直接注射化疗药物治疗癌性肺不张28例,与常规疗法22例对照,疗效明显,报道如下。1 资料与方法1.1 一般资料 本组50例,男32例、女18例,年龄31～69岁,平均年龄51.5岁;均符合下列条件:①咳嗽、咯痰、咯血、呼吸困难等症状;②痰查瘤细胞阳性;③胸片或CT均诊为癌性肺不张,其中大叶不张18例,段性不张24例,一侧全肺不张8例;④肺功能检查示肺活量减低;⑤纤支镜检查示原发性支气管肺癌,
Epidemiological data show that the incidence of lung cancer in our country showed an upward trend, including cancer atelectasis as high as 60.5% to 80%, conventional chemotherapy and more systemic chemotherapy, local radiotherapy, etc., the effect is not satisfied, and side effects. After more than two years of efforts, our hospital has directly injected chemotherapeutic drugs to the tumor tissue to treat 28 cases of cancerous atelectasis under direct vision with fiberoptic bronchoscope (hereinafter referred to as bronchoscopy). Compared with conventional therapy, 22 cases have obvious curative effect. The report is as follows. 1 Materials and Methods 1.1 General Information The group of 50 patients, 32 males and 18 females, aged 31 to 69 years, mean age 51.5 years; both meet the following conditions: 1 cough, expectoration, hemoptysis, dyspnea and other symptoms; 2 Check the tumor cells were positive; 3 chest X-ray or CT were diagnosed as cancerous atelectasis, including 18 cases of atelectasis, 24 cases of atelectasis, atelectasis in 8 cases on one side; 4 pulmonary function tests showed vital capacity Reduce; 5 bronchoscopy examination showed primary bronchial cancer,