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目的探讨体力活动与卵巢早衰发病之间的关系,以便在体力活动方面为卵巢早衰的预防提供依据。方法收集2015年11月-2017年1月于某院生殖内分泌门诊就诊的患者,确定病例组与对照组研究对象,分析2组间体力活动状况的差异,探讨体力活动与卵巢早衰发病之间的关系。结果共纳入卵巢早衰组70例,对照组224例。单因素和多因素分析结果显示,低身体活动水平是卵巢早衰发病的潜在危险因素,而高静息代谢率则是潜在减少卵巢早衰发生的有益因素[(OR值分别为5.917(95%CI:1.446~24.207)和0.048(95%CI:0.005~0.489)]。结论低体力活动可能导致卵巢早衰的发病,适当运动提高静息代谢率则可能一定程度上降低卵巢早衰的发生。
Objective To explore the relationship between physical activity and the incidence of premature ovarian failure in order to provide a basis for the prevention of premature ovarian failure in physical activity. Methods From November 2015 to January 2017, patients from a reproductive endocrinology clinic in a hospital were enrolled. The subjects in the case group and the control group were determined. The differences in physical activity between the two groups were analyzed to explore the relationship between physical activity and premature ovarian failure relationship. Results A total of 70 cases of premature ovarian failure and 224 cases of control group were included. Univariate and multivariate analysis showed that low physical activity level was a potential risk factor for premature ovarian failure, whereas high resting metabolic rate was a potential benefit for potentially reducing the incidence of premature ovarian failure (OR, 5.917, 95% CI: 1.446 ~ 24.207) and 0.048 (95% CI: 0.005 ~ 0.489) .Conclusion Low physical activity may lead to the development of premature ovarian failure. Appropriate exercise to increase the resting metabolic rate may reduce the occurrence of premature ovarian failure to a certain extent.