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慢性肾脏疾病(chronic kidney diseaseCKD)常存在胰岛素抵抗(insulin resistance,IR)和高胰岛素血症,并且在慢性肾脏疾病的早期即可出现,多种因素在慢性肾脏疾病胰岛素抵抗的发生、发展中起重要作用。慢性肾病患者出现IR后,随着IR的增加,肾功能出现下降。深入探究IR与肾脏疾病之间的关系,已经成为当前糖尿病和肾病领域共同面临的重要课题。本文就IR与慢性肾脏疾病的关系及对IR的防治进行综述。
Chronic kidney disease (CKD) is often associated with insulin resistance (IR) and hyperinsulinemia and occurs early in chronic kidney disease. Various factors play an important role in the development and progression of insulin resistance in chronic kidney disease Important role. In patients with chronic kidney disease after IR, with the increase of IR, renal function decline. In-depth study of the relationship between IR and kidney disease has become an important issue in the field of diabetes and nephropathy. This article reviews the relationship between IR and chronic kidney disease and the prevention and treatment of IR.