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目的探讨伴有软骨黏液样纤维瘤样形态特征骨肉瘤(CMFL OS)的临床病理学特征及鉴别诊断。方法分析1例CMFL OS的临床及影像学资料,观察其病理学形态,并复习相关文献探讨该肿瘤的病理诊断及鉴别诊断要点。结果患者男性,39岁。发现左大腿肿物5个月。磁共振示髓腔密度不均,伴软组织包块。镜下组织呈分叶状结构,肿瘤组织由梭形及星形细胞组成,细胞轻~中度异型,可见不规则成骨。结论伴有软骨黏液样纤维瘤样形态特征的骨肉瘤是普通型骨肉瘤的一种亚型,较为罕见,组织学和影像学检查对本病的诊断具有重要的作用。
Objective To investigate the clinicopathological features and differential diagnosis of CMFOs with cartilage myxoid fibroid tumor. Methods 1 case of CMFL OS clinical and imaging data to observe the pathological morphology, and review the literature to explore the pathological diagnosis of the tumor and the main points of differential diagnosis. Results The patient was male, 39 years old. Left thigh tumor was found for 5 months. MRI showed uneven density of the marrow cavity, with soft tissue mass. Microscopic lobular structure was organized, the tumor tissue by the spindle and astrocytes, light to moderately shaped cells, showing irregular osteophytes. Conclusion Osteosarcoma with cartilage myxoma-like morphological features is a subtype of common osteosarcoma, which is rare. Histological and imaging examination plays an important role in the diagnosis of this disease.