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用大剂量环磷酰胺 (cyclophosphamide ,CY)及全身照射(totalbodyirradiation ,TBI)作为预处理方案进行骨髓移植 ,绝大多数患者术后伴发终身不育症[1] 。对此类病人而言 ,生育能力的恢复十分少见 ,男性患者尤为如此。我们曾收治一例男性患者 ,用CY +TBI方案预处理进行自体骨髓移
High-dose cyclophosphamide (CY) and total body irradiation (TBI) were used as pretreatment regimens for bone marrow transplantation, and most patients have postoperative lifelong infertility [1]. For such patients, fertility recovery is very rare, especially in males. We treated a male patient who underwent autologous bone marrow mobilization with a CY + TBI regimen