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[Objective] To determine the optimum harvest time of FRUCTUS EVODIAE. [Method] The optimum harvest time of FRUCTUS EVODIAE was determined according to the apparent characteristics and the content of evodine, evodiamine and rutaecarpine in FRUCTUS EVODIAE by high-performance liquid chromatography (HPLC). [Result] In the investigated harvest time, the content change of evodine was insignificant, and the content of evodiamine and rutaecarpine first increased then slowly declined with the harvest time. [Conclusion] The proposed method was simple, rapid, accurate and reliable, and can be used as a tool for quality control of FRUCTUS EVODIAE. The optimum harvest time was during mid-to-late August.
[Method] The optimum harvest time of FRUCTUS EVODIAE was determined according to the apparent characteristics and the content of evodine, evodiamine and rutaecarpine in FRUCTUS EVODIAE by high-performance liquid chromatography (HPLC ) [Result] In the investigated harvest time, the content change of evodine was insignificant, and the content of evodiamine and rutaecarpine first increased then slowly declined with the harvest time. [Result] The proposed method was simple, rapid, accurate and reliable , and can be used as a tool for quality control of FRUCTUS EVODIAE. The optimum harvest time was during mid-to-late August.