Carotid body-mediated changes of sympathetic nerve and their relationships with hypertension

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Hypoxia is encountered under many physiological and pathophysiological situations. Although both intermittent hypoxia (IH) and continuous hypoxia (CH)result in decreases in arterial O2,there are striking differences in the response of the physiological systems to CH and IH.Obstructive sleep apnea-hypopnea syndrome (OSAHS),characterized by frequently recurrent intermittent hypoxia/reoxygenation (IH/ROX)as its obvious pathological trait,is clearly associated with an increased risk of cardiovascular disorders,particularly hypertension,1 and IH/ROX may be the primary pathological basis for OSAHS complicated hypertension.2
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