硫酸小诺霉素注射液的含量测定,主要采用微生物检定法和旋光法。其中微生物检定准确可靠,不过操作繁琐费时,不适合于快速分析的需要。本文采用碱性酒石酸铜比色法测定了硫酸小诺霉素注射液的含量并与微生物检定法进行了比较,结果满意。 1 仪器与试药:岛津UV—265型紫外可见分光光度计(日本岛津);硫酸小诺霉素标准品(卫 Determination of the content of minocycline sulfate injection, the main use of microbiological assay and optical rotation method. Microbiological examination which is accurate and reliable, but cumbersome and time-consuming operation, not suitable for rapid analysis needs. In this paper, copper tartrate colorimetric method was used to determine the content of minocycline sulfate injection and compared with the method of microbe test, the result was satisfactory. 1 instruments and reagents: Shimadzu UV-265 UV-visible spectrophotometer (Japan Shimadzu); small nitric acid sulfate standard