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目的观察硫酸镁联合拉贝洛尔治疗妊娠期高血压的临床疗效果。方法选取医院2013年6月-2015年9月住院的妊娠期高血压患者120例,按照患者的具体病情分为观察组和对照组各60例,对照组给予硫酸镁治疗,观察组在对照组治疗基础上,加用拉贝洛尔治疗,治疗1个月后,观察2组的临床效果,血压情况及不良反应情况。结果 2组治疗后,SBP、DBP均低于治疗前,且观察组治疗后明显低于对照组(P<0.05)。观察组总有效率为91.6%明显高于对照组的76.7%(P<0.05)。观察组并发症发生率为16.7%明显低于对照组的30.0%,差异均有统计学意义(P<0.05)。结论硫酸镁联合拉贝洛尔治疗妊娠期高血压疾病效果显著,并发症少,拉贝洛尔可有效避免硫酸镁的血压反跳情况,使孕产妇血压稳定时间更长,值得临床推广应用。
Objective To observe the clinical efficacy of magnesium sulfate and labetalol in the treatment of gestational hypertension. Methods Totally 120 hypertensive patients admitted to hospital from June 2013 to September 2015 were divided into observation group and control group according to their specific conditions. The control group was treated with magnesium sulfate. In the control group On the basis of treatment, plus labetalol treatment, after 1 month of treatment, the clinical effects, blood pressure and adverse reactions in 2 groups were observed. Results After treatment, SBP and DBP in both groups were lower than before treatment, and the observation group was significantly lower than the control group after treatment (P <0.05). The total effective rate in the observation group was 91.6%, which was significantly higher than that in the control group (76.7%, P <0.05). The complication rate in observation group was significantly lower than that in control group (16.7% vs 30.0%, P <0.05). Conclusions Magnesium sulphate and labetalol are effective in treating hypertensive disorder complicating pregnancy. There are few complications. Labetalol can effectively prevent the rebound of magnesium sulfate and stabilize the blood pressure of pregnant women for a long time, which is worthy of clinical application.