[作用]本品为可供口服的长效抗心律失常药,其电生理作用类似于奎尼丁和普鲁卡因酰胺。它能减慢心脏传导系统各部分的传导,降低膜反应性,提高兴奋阈值,延长心房、房室结、希氏-浦倾野系统和心室的有效不应期,阻滞旁路的前向和逆向传导。本品对小鼠腹腔注射的半数致死量为62.7 mg/kg,对家兔静脉注射的平均致死量为9.8mg/kg。药理实验表明,本品对因注射乌头碱引起的大鼠实验性心律失 [Effect] This product is available for oral long-acting antiarrhythmic drugs, its electrophysiological effects similar to quinidine and procainamide. It slows down the conduction of various parts of the heart’s conduction system, decreases membrane reactivity, increases excitation thresholds, prolongs the effective refractory period of the atria, atrioventricular node, And reverse conduction. This product of mice by intraperitoneal injection of the lethal dose was 62.7 mg / kg, the average intravenous injection of rabbit lethal dose of 9.8mg / kg. Pharmacological experiments show that the goods due to injection of aconitine induced experimental arrhythmia in rats