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目的:观察胰岛素增敏剂二胛双胍治疗对非酒精性脂肪肝病(NAFLD)的治疗作用。方法:随机将84例NAFLD患者分为治疗组和对照组,两组均给予常规运动和饮食治疗,对照组42例服用维生素C和维生素E;治疗组42例服用二胛双胍两组疗程均为6个月。结果:治疗组患者的TC,TG,ALT,AST,GGT,肝胆B超均较对照组有明显改善。有显著性差异,P<0.05。结论:在常规饮食治疗和运动治疗的同时治疗组用二胛双胍对照组用维生素C和维生素E,治疗NAFCD,治疗组治疗效果明显优于对照组,且副作用小。
OBJECTIVE: To observe the therapeutic effect of insulin diphosteride, an insulin sensitizer, on non-alcoholic fatty liver disease (NAFLD). Methods: Eighty-four patients with NAFLD were randomly divided into treatment group and control group. Both groups were given routine exercise and diet. In the control group, 42 patients took vitamin C and vitamin E. In the treatment group, 42 patients treated with sodium sulphate twice 6 months. Results: The TC, TG, ALT, AST, GGT and hepatobiliary B in the treatment group were significantly improved compared with the control group. There was a significant difference, P <0.05. CONCLUSION: In the treatment group with conventional diet therapy and exercise therapy, the treatment with sodium-sulphadiazine and vitamin E and vitamin E were effective in the treatment of NAFCD. The therapeutic effect of the treatment group was significantly better than that of the control group, and the side effects were small.