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目的:探讨肺部念珠菌感染的危险因素、临床诊断、治疗及预后。方法:回顾性分析112例呼吸道念珠菌感染的临床资料。结果:呼吸道念珠菌感染的危险因素为:长期使用广谱抗菌药物及糖皮质激素、免疫抑制剂,以肾移植术后、慢性阻塞性肺疾病、支气管扩张、白血病等慢性基础疾病病人多见。结论:合理使用抗菌药物及糖皮质激素、免疫抑制剂,以及早期诊断和及时抗真菌治疗,是降低呼吸道念珠菌感染并降低病死率的重要措施。
Objective: To investigate the risk factors, clinical diagnosis, treatment and prognosis of Candida albicans in lung. Methods: A retrospective analysis of 112 cases of respiratory Candida infection clinical data. Results: The risk factors of Candida albicans infection were long-term use of broad-spectrum antibiotics and glucocorticoids, immunosuppressive agents, and chronic prostatitis, chronic obstructive pulmonary disease, bronchiectasis, leukemia and other chronic diseases. Conclusion: The rational use of antibiotics and glucocorticoids, immunosuppressive agents, and early diagnosis and timely antifungal therapy are important measures to reduce respiratory candidosis and reduce mortality.