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目的研究妊娠对青年乳腺癌患者预后的影响。方法选取郑州人民医院2010年1月至2013年6月158例青年乳腺癌患者为研究对象,根据妊娠情况将患者分为妊娠组和未妊娠组,妊娠组39例,未妊娠组119例,比较两组3年无病生存率和3年总生存率。结果妊娠组3年无病生存率和3年总生存率分别为59.0%、69.2%,显著高于未妊娠组的34.5%、42.0%(P<0.05)。结论妊娠不会增加青年乳腺癌患者肿瘤复发、转移、死亡的风险,可以根据患者的具体病情对患者的生育要求进行建议和指导。
Objective To study the effect of pregnancy on the prognosis of young patients with breast cancer. Methods A total of 158 young patients with breast cancer from January 2010 to June 2013 in Zhengzhou People’s Hospital were enrolled. According to the pregnancy status, the patients were divided into pregnancy group and non-pregnancy group. There were 39 pregnant women and 119 non-pregnant women. Two groups of 3-year disease-free survival rate and 3-year overall survival rate. Results The 3-year disease-free survival rate and 3-year overall survival rate in pregnancy group were 59.0% and 69.2% respectively, significantly higher than those in non-pregnant group (34.5% and 42.0%, P <0.05). Conclusion Pregnancy does not increase the risk of tumor recurrence, metastasis and death in young patients with breast cancer. According to the specific condition of the patient, the patient’s fertility requirements can be suggested and guided.