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用放射免疫法（ＲＩＡ）检测了４０例正常人及６６例食管癌患者放疗前后血浆Ｐｉ类谷胱甘肽Ｓ－转移酶（ＧＳＴ－π）水平。结果显示：食管癌患者放疗前血浆ＧＳＴ－π水平显著高于正常对照（Ｐ＜０．００１），且水平和食管病变长度呈正相关。放疗后血浆ＧＳＴ－π水平显著降低（Ｐ＜０．０１），其水平在完全缓解（ＣＲ）病例与正常对照无明显差异（Ｐ＞０．０５），在部分缓解（ＰＲ）病例仍高于正常对照（Ｐ＜０．００１）。说明食管癌患者血浆ＧＳＴ－π水平与其肿瘤的消长密切相关，有可能成为疗效和判断预后的一个监测指标。
Radioimmunoassay (RIA) was used to detect plasma levels of Pi glutathione S-transferase (GST-π) in 40 normal subjects and 66 patients with esophageal cancer before and after radiotherapy. The results showed that plasma levels of GST-π in patients with esophageal cancer before radiotherapy were significantly higher than those in normal controls (P<0.001), and the levels were positively correlated with the length of esophageal lesions. The plasma GST-π levels were significantly lower after radiotherapy (P<0.01), and the levels were not significantly different between complete remission (CR) cases and normal controls (P>0.05), and were still higher in partial remission (PR) cases. Normal control (P<0.001). It shows that plasma GST-π levels in patients with esophageal cancer are closely related to the growth and decline of tumors, and may be a monitoring indicator for efficacy and prognosis.