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目的:探讨不同强度运动处方在8周减肥过程中对青春期肥胖大鼠运动后即刻能耗、体重和Lee’s的影响。方法:大鼠建模7周后,取32只肥胖鼠随机分为4组,每组8只,分别为肥胖对照组、低强度运动组、中强度运动组、高强度运动组。3种强度在动物跑台跑速分别定为15-18m/min、21-25 m/min、28-32 m/min,5次/周,60min/次,持续8周。每周测体重、计算Lee’s指数,采用大鼠代谢系统测大鼠运动后即刻吸氧量以及能量消耗。结果:8周干预过程中,干预各组表现出运动后即刻的肌肉吸氧量和总吸氧量、肌肉能耗和总能耗明显高于对照组(P<0.05,P<0.01),高强度组高于低强度组(P<0.05);体重表现为干预组增长幅度明显低于对照组(P<0.05,P<0.01),Lee’s指数表现为干预组在第8周均低于对照组(P<0.05,P<0.01),不同强度运动之间无明显差异(P>0.05)。结论:青春期肥胖大鼠伴随周龄的增加体重呈上升趋势,而肌肉吸氧量和总吸氧量、肌肉能耗和总能耗呈下降趋势。经过8周运动干预后,不同强度运动处方能提高青春期肥胖大鼠运动后即刻的吸氧量及能量消耗,高强度运动的效果最明显;而体重的增长幅度及Lee’s指数均有所降低,但受运动强度的影响较小。
OBJECTIVE: To investigate the effects of different exercise prescriptions on energy consumption, body weight and Lee’s after exercise in adolescent obese rats during 8-week weight loss. Methods: After 7 weeks of modeling, 32 obese mice were randomly divided into 4 groups with 8 rats in each group. They were obese control group, low-intensity exercise group, moderate-intensity exercise group and high-intensity exercise group. The three kinds of intensities were set at 15-18m / min, 21-25m / min, 28-32m / min, 5 times / week and 60min / time in animal treadmill respectively for 8 weeks. Body weight was measured weekly and Lee’s index was calculated. Rat oxygen metabolism and energy expenditure were measured immediately after exercise. Results: In the course of 8 weeks intervention, the muscle oxygen consumption and total oxygen uptake, muscular energy consumption and total energy consumption of the intervention group were significantly higher than those of the control group immediately after exercise (P <0.05, P <0.01) (P <0.05). The body weight of the intervention group was significantly lower than that of the control group (P <0.05, P <0.01). The Lee’s index was lower in the intervention group than in the control group (P <0.05, P <0.01). There was no significant difference between different intensity exercises (P> 0.05). Conclusion: The body weight of adolescent obese rats increased with the increase of age, and muscle oxygen consumption and total oxygen uptake, muscle energy consumption and total energy consumption decreased. After 8 weeks of exercise intervention, different intensity exercise prescriptions can increase the oxygen uptake and energy consumption of adolescent obese rats immediately after exercise, and the effect of high-intensity exercise was most obvious. However, the increase of body weight and Lee’s index decreased, however, Less affected by exercise intensity.