血清抗胰蛋白酶(α_1AT)为肝细胞合成的一种重要蛋白酶抑制剂,肝癌细胞亦能合成,由于此低分子量糖蛋白异常与肝病相关,在过去五年中,本实验室建立了血清α_1AT检测方法,观察到对AFP阴性肝癌诊断颇有价值,本文着重评价其对良恶性肝病鉴别诊断的意义。 材料与方法 α_1AT抗血清系本实验室自行制备,其效价为1:128。电泳缓冲液为巴比妥钠—盐酸pH8.6。火 Serum anti-trypsin (α_1AT) is an important protease inhibitor for the synthesis of hepatocytes. Hepatoma cells can also be synthesized. Due to the abnormality of this low-molecular-weight glycoprotein and liver disease, serum α_1AT was established in our laboratory in the past five years. Methods. It was observed that the diagnosis of AFP-negative liver cancer is quite valuable. This article focuses on the evaluation of its significance for the differential diagnosis of benign and malignant liver diseases. Materials and Methods α_1AT antiserum was prepared by our laboratory and its titer was 1:128. The electrophoresis buffer was pentobarbital-hydrochloric acid pH8.6. fire