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In 1928 Fleming observed the antibacterial action of penicillin at St.Maryt’s Hospital, London, on a plate seeded with staphylococci that had been contaminated with a strain of penicillium natatum.More than ten years later H. W. Florey and E. Chain and their colleagues at Oxford University showed that crude preparations of penicillin had chemotherapeutic properties which seemed at the time to be almost miraculous. This marked the beginning of investigations that were to lead to the widespread use of β-lactam antibiotics in medicine.
In 1928 Fleming observed the antibacterial action of penicillin at St. Mary’s Hospital, London, on a plate seeded with staphylococci that had been contaminated with a strain of penicillium natatum. More than ten years later HW Florey and E. Chain and their colleagues at Oxford University showed that crude preparations of penicillin had chemotherapeutic properties which seemed at the time to be almost miraculous. This marked the beginning of investigations that were to lead to the widespread use of β-lactam antibiotics in medicine.