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目的了解重庆市肿瘤登记地区结直肠肛门癌发病趋势变化及其影响因素,为开展结直肠肛门癌防治工作提供建议。方法收集整理2006—2014年重庆市肿瘤登记点报告结直肠肛门癌新发病例,统计分析发病率、中国人口标化发病率(中标率)、年度变化百分比,采用曲线估计指数分布回归模型进行趋势变化分析。采用差别分解法计算出人口因素和非人口因素对恶性肿瘤发病的贡献率。结果重庆市结直肠肛门癌发病率和中国人口标化发病率由2006年的14.15/10万和12.57/10万上升至26.82/10万与17.67/10万,年度变化百分比(APC)分别为8.22%与4.39%,变化趋势差异有统计学意义(P<0.05)。城市与农村发病率及中标率均呈上升的趋势,差异均有统计学意义(P<0.05)。重庆市结直肠肛门癌发病率上升人口因素与非人口因素的贡献率分别为56.72%与43.28%,城市地区结直肠肛门癌发病率上升非人口因素的贡献率(66.94%)高于人口因素的贡献率(33.06%),而农村地区结直肠肛门癌发病率上升人口因素的贡献率(78.76%)高于非人口因素的贡献率(21.24%)。结论重庆市结直肠肛门癌发病率呈持续上升的趋势,受人口因素与非人口因素的协同影响,应针对城乡影响因素的差异开展结直肠肛门癌的防治工作。
Objective To investigate the incidence of colorectal anorectal cancer in Chongqing area and its influencing factors, and to provide recommendations for the prevention and treatment of colorectal anorectal cancer. Methods The cases of newly diagnosed colorectal anorectal cancer in Chongqing Cancer Registry from 2006 to 2014 were collected and analyzed. The incidence of colorectal anorectal cancer was statistically analyzed, and the incidence rate of Chinese population standardization (the successful bidding rate) and the percentage of annual change were collected. The trend of the regression model was estimated by using the curve estimated exponential distribution Change Analysis. The differential decomposition method was used to calculate the contribution rate of population factors and non-population factors to the incidence of malignant tumors. Results The incidence of colorectal anorectal cancer in Chongqing and the incidence of population standardization in China increased from 14.15 / 100,000 and 12.57 / 100,000 in 2006 to 26.82 / 100000 and 17.67 / 100,000 respectively, and the annual percentage changes (APC) were 8.22 % And 4.39% respectively, with significant difference (P <0.05). The morbidity and successful rate in both urban and rural areas tended to increase, with statistical significance (P <0.05). The contribution rates of colorectal anorectal cancer in Chongqing from non-population factors to non-population factors were 56.72% and 43.28% respectively. The contribution rate of non-population factors to colorectal anorectal cancer in urban areas was 66.94% higher than that of population factors (33.06%), while the incidence of colorectal anorectal cancer in rural areas was higher (78.76%) than that of non-population factors (21.24%). Conclusions The incidence of colorectal anorectal cancer in Chongqing is on the rise. Due to the synergistic effect of population factors and non-population factors, the prevention and treatment of colorectal anorectal cancer should be carried out according to the differences of urban and rural factors.