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我们曾报告灵芝制剂“薄醇水”与“孢醇水”对神经系统的影响,及“薄醇醚”与“孢醚”的保肝解毒作用 (中华医学杂志57(10):607,1977)。由于几个医院发现薄醇水及孢醇水对进行性肌营养不良等肌病有一定治疗效果,我们与植化室合作,对薄醇水的有效成分进行了研究。根据进行性肌营养不良病人和遗传性肌营养不良动物血清醛缩酶活性明显升高,及国外常用2,4-二氯苯氧乙酸(2,4-D)复制动物肌强直症的事实,我们发现皮下注射2,4-D 150mg/kg 能使小鼠血清醛缩酶明显升高。如于注射2,4-D 前半小时及注射
We have reported on the effects of ganoderma lucidum preparations, thin alcohol, and spore alcohol on the nervous system, and the hepatoprotective and detoxifying effects of thin alcohol ether and spore ether (Chinese Journal of Medicine) 57(10):607, 1977). Since several hospitals have found that thin alcohol water and spirulina water have a certain therapeutic effect on myopathy such as progressive muscular dystrophy, we cooperated with the plantation room to study the active ingredients of thin alcohol water. According to the fact that the activity of serum aldolase in patients with progressive muscular dystrophy and hereditary muscular dystrophy is significantly elevated, and the fact that 2,4-dichlorophenoxyacetic acid (2,4-D) is commonly used abroad to replicate animal myotonia, We found that subcutaneous injection of 2,4-D 150mg/kg can significantly increase serum aldolase in mice. For example, half an hour before the injection of 2,4-D and injection