论文部分内容阅读
目的:探讨消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素(PGF2α)和血清卵巢癌表面抗原(CA125)的影响。方法:实验分为生理盐水组,西药对照组,中药高剂量组,中药低剂量组,每组10只,采用ELISA法,观察子宫内膜异位症模型大鼠腹腔液PGF2α血清CA125水平浓度。结果:消癥汤能够降低子宫内膜异位症模型鼠血清CA125水平和腹腔液中PGF2α含量,对异位子宫内膜具有一定的抑制作用。结论:消癥汤能降低血清CA125水平、腹腔液中PGF2α含量,抑制异位子宫内膜的异常增生。
Objective: To investigate the effect of Xiaoshi Decoction on peritoneal fluid prostaglandin (PGF2α) and serum ovarian cancer surface antigen (CA125) in endometriosis model rats. Methods: The experiment was divided into saline group, western medicine control group, traditional Chinese medicine high-dose group and traditional Chinese medicine low-dose group, with 10 rats in each group. Serum levels of CA125 in peritoneal fluid of endometriosis model rats were measured by ELISA. Results: Xiaozheng decoction can reduce serum CA125 level and PGF2α content in peritoneal fluid of endometriosis model rats, and have certain inhibitory effect on ectopic endometrium. Conclusion: Xiaoyan decoction can reduce the level of serum CA125, the content of PGF2α in peritoneal fluid and inhibit the abnormal proliferation of ectopic endometrium.