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选择了100例正切的食管活检标本进行了组织形态测量。100个受检者中,内镜诊断慢性食管炎者45例,诊断正常者55例。测量结果表明,上皮厚度在慢性食管炎与正常对照组间有明显的不同(P<0.05),基底细胞层厚度在中度食管炎与对照组间也有明显的差异(P<0.05),但是,乳头高度、乳头相对高度和中性白细胞浸润程度在两组间没有区别,因而认为,食管上皮厚度和基底细胞层厚度的改变可以作为用测量方法诊断慢性食管炎和估价食管癌前病变的一个客观指标。
100 cases of tangential esophageal biopsy specimens were selected for histomorphometric measurements. Of the 100 subjects, 45 were diagnosed as chronic esophagitis by endoscopy and 55 were diagnosed as normal. The measurement results showed that the epithelium thickness was significantly different between chronic esophagitis and normal controls (P<0.05), and the basal cell thickness was also significantly different between moderate esophagitis and the control group (P<0.05). Nipple height, relative nipple height, and neutrophil infiltration degree did not differ between the two groups. Therefore, it was considered that changes in esophageal epithelium thickness and basal cell layer thickness can be used as an objective method for diagnosing chronic esophagitis and evaluating esophageal precancerous lesions by measurement methods. index.