自从1951年 Reed 从肝渣中分离出结晶的硫辛酸以来,硫辛酸类化合物就因其具有很强的生物活性和分子中含有特殊的双硫五元环结构而引起人们的重视。多年来国内外已将这类化合物用于辐射药物防护研究中,获得一定的防护效价。但是其防护作用原理还不清楚,并未见其早期直接防护作用的研究报告。这类化合物易于聚合为不同 Since the separation of crystalline lipoic acid from liver residue by Reed in 1951, lipoic acid compounds have drawn great attention because of their strong biological activity and the unique five-membered ring structure in their molecules. Over the years, these compounds have been used in the research of radiation medicine protection both at home and abroad, obtaining some protection potency. However, its protective principle is not clear, and did not see the early direct protective effect of the study. Such compounds tend to polymerize differently