论文部分内容阅读
目的观察急性Vogt-小柳原田综合征(VKH综合征)频域相干光断层扫描(SpectralisOCT)黄斑区结构改变特征。设计前瞻性病例系列。研究对象连续收集北京同仁医院急性期VKH综合征确诊病例10例(20眼)。方法所有病例均接受详细的病史采集,以及视力、裂隙灯显微镜、间接检眼镜和荧光素眼底血管造影等检查。频域OCT检查于就诊当日完成,此后每2～7日进行定位随诊模式OCT扫描,直至患者黄斑区视网膜完全复位。荧光素眼底血管造影和OCT阅片诊断由同一名眼底病医师独立完成。主要指标定性描述OCT下黄斑区视网膜各层结构变化特点。结果间接检眼镜下所有VKH综合征患者均可见后极部多湖状浆液性视网膜脱离。OCT检查显示4例8眼(40%)表现为视网膜神经上皮脱离型改变,2例4眼(20%)为视网膜神经上皮外层劈裂型改变,4例8眼(40%)呈混合型改变。结论急性VKH综合征患者黄斑区多湖样浆液性视网膜脱离是视网膜神经上皮脱离与视网膜神经上皮外层水肿或劈裂的共同结果。
Objective To observe the structural changes in the macular area of the SpectralisOCT in acute Vogt-Koyanagi-Haiten Syndrome (VKH syndrome). Design prospective case series. The subjects were consecutively collected 10 cases (20 eyes) of confirmed cases of VKH syndrome in Beijing Tongren Hospital. Methods All patients underwent detailed history acquisition and visual acuity, slit lamp microscopy, indirect ophthalmoscopy and fluorescein angiography. Frequency domain OCT examination completed on the day of treatment, then every 2 to 7 days follow-up mode OCT scan, until the patient’s macular retina completely reset. Fundus fluorescein angiography and OCT reading diagnosis by the same physician independently done. The main indicators qualitative description of the OCT macular retinal layer structure changes. Results All patients with VKH syndrome under indirect ophthalmoscope showed lacustrine serous retinal detachment in the posterior pole. OCT examination showed retinal neuroepithelial detachment in 4 eyes (40%), retinal neuroepithelial dehiscence in 2 (4 eyes) (20%), hybridization in 4 eyes (40%) change. Conclusions The lake-like serous retinal detachment in patients with acute VKH syndrome is a common result of retinal neuroepithelial detachment and retinal neuroepithelial edema or cleavage.