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目的分析探讨一氧化碳中毒后迟发性脑病的发病特征与机制,总结临床诊治经验。方法收集我院2007年1月至2011年1月期间因急性一氧化碳中毒迟发性脑病住院的患者共76例,对其临床资料进行回顾性调查分析。结果患者有众多临床表现:精神淡漠、痴呆、小便失禁、缄默、偏瘫、癫痫发作等;76例患者治疗后经疗效判定,其中治愈24例,显效26例,好转12例,无效14例,总有效率为81.6%。结论 DEACMP发病机制尚不明了,临床表现众多,影像学检查有助于提高对患者的诊断,减少误诊率,给予患者及时、足疗程的治疗可最大限度的促进患者预后。
Objective To analyze the characteristics and mechanism of delayed encephalopathy after carbon monoxide poisoning and to summarize the experience of clinical diagnosis and treatment. Methods A total of 76 patients hospitalized for delayed encephalopathy caused by acute carbon monoxide poisoning during our hospital from January 2007 to January 2011 were retrospectively analyzed. Results There were many clinical manifestations in patients: apathetic, dementia, urinary incontinence, silent, hemiparesis, seizures and so on; 76 patients after treatment were judged by curative effect, of which 24 were cured, 26 were markedly effective, 12 improved, 14 ineffective, The effective rate is 81.6%. Conclusions The pathogenesis of DEACMP is still unknown. There are many clinical manifestations. Imaging examination can help to improve the diagnosis of patients and reduce the misdiagnosis rate. To give timely and full treatment to patients can maximize the prognosis of patients.