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目的分析2007年广州市流行性感冒的流行特征。方法监测来自广州市3家监测医院的流感样病例的漱口液或咽拭子标本,采用MDCK细胞进行病毒分离,通过红细胞凝集实验和红细胞凝集抑制实验进行鉴定;按0~、5~、15~、25~、60~以上5个年龄组分层随机抽取健康人群的血清标本,采用红细胞凝集抑制实验检测血清中的各型流感抗体。结果全年共对1068份流感样病例标本进行了病毒分离,共分离出46株流感病毒,分离率为4.3%,其中H3N2型15株(32.6%),B(Yamagata)型27株(58.7%),B(Victoria)型4株(8.7%),未分离出H1N1型流感病毒株。60~组人群的病毒分离率最高,为7.7%;健康人群血清中流感抗体的阳性率不高,最高为10月份H3N2的抗体阳性率,为44%,最低为3月份B(Yamagata)的抗体阳性率,仅为6.7%。结论2007年广州市流感病毒的流行时间有明显的季节性,流感病毒的活动相对平缓,B(Yamagata)型流感病毒是2007年的优势株,主要是在夏季和25~岁组的人群中流行。流感对老年人的威胁最大,有必要针对老年人加强流感的预防工作。
Objective To analyze the epidemic characteristics of influenza in Guangzhou in 2007. Methods Mouthwash or throat swab specimens were collected from three flu surveillance hospitals in Guangzhou City. MDCK cells were used for virus isolation and identified by erythrocyte agglutination test and hemagglutination inhibition test. According to 0 ~, 5 ~, 15 Serum samples of healthy population were randomly selected from 5 ~ ~ 25 ~ 60 ~ 5 age groups, and all kinds of influenza antibodies in serum were detected by hemagglutination inhibition test. Results A total of 1068 influenza-like samples were isolated during the year. A total of 46 influenza viruses were isolated and the isolation rate was 4.3%, of which 15 (32.6%) were H3N2 and 27 (58.7%) were B (Yamagata) ) And 4 (8.7%) strains of type B (Victoria). No H1N1 influenza virus strains were isolated. In 60 ~ group, the highest virus isolation rate was 7.7%. The positive rate of influenza antibody in healthy people was not high, the highest was the antibody positive rate of H3N2 in October, 44%, the lowest was the antibody of B (Yamagata) in March The positive rate, only 6.7%. Conclusions The epidemic time of influenza virus in Guangzhou was obviously seasonal in 2007, and the activity of influenza virus was relatively flat. Yamagata influenza B virus was the predominant strain in 2007, and was predominant in summer and 25 ~ . The flu poses the greatest threat to the elderly and there is a need to step up flu prevention in the elderly.