论文部分内容阅读
目的探讨粉尘作业人员发生肺动脉高压(PAH)的影响因素。方法选取工种、接尘时间、融合块形成以及肺气肿征象、肺大泡、继发性肺结核等尘肺病常见并发症为观察指标,进行非条件Logistic回归分析。多分类变量进行组内对照比较。结果粉尘作业人员发生PAH的独立危险因素包括:工种(P=0.036,OR=1.134)、接尘时间(P=0.016,OR=1.145)、融合块形成(P=0.001,OR=1.777)、肺气肿征象(P=0.004,OR=1.679)、继发性肺结核(P=0,OR=2.065)。工种组内比较显示,石匠与石料开采加工、石英砂接尘组发生PAH的可能性是其他组的1.59~2.545倍。随着接尘时间的增长,发生PAH的可能性成倍增加。结论接尘工人出现肺气肿征象、继发性肺结核等并发症应及时进行临床干预,阻止PAH的进展;不同工种的危险性、接尘时间的累积效应、融合块形成是预防PAH和改善预后中应引起重视的因素。
Objective To investigate the influencing factors of pulmonary hypertension (PAH) in dust workers. Methods The common complications of pneumoconiosis such as trauma, dusting time, the formation of fusion mass, signs of emphysema, bullae and secondary pulmonary tuberculosis were selected as the observation indexes, and non-conditional logistic regression analysis was performed. Multi-category variables were compared within the group. Results The independent risk factors of PAH among dust workers were as follows: type of work (P = 0.036, OR = 1.134), dusting time (P = 0.016, OR = 1.145) Signs of emphysema (P = 0.004, OR = 1.679), secondary pulmonary tuberculosis (P = 0, OR = 2.065). Comparison of types of work group shows that stonemasons and stone mining processing, quartz sand dusting group PAH possibility is 1.59 ~ 2.545 times the other groups. With the increase of dusting time, the possibility of PAH increased exponentially. Conclusion The workers exposed to dust have signs of emphysema, complications such as secondary pulmonary tuberculosis should timely clinical intervention to prevent the progression of PAH; the risk of different types of work, the cumulative effect of dust exposure time, the formation of fusion blocks is to prevent PAH and improve prognosis Should pay attention to the factors.