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正常脑脊液中可以测得 IgG。虽然 IgA 含量甚微,目前亦能检出。IgM 是一种巨球蛋白,分子量软大,为900,000,正常人由于血脑屏障的作用,IgM 不易穿透,因此,脑脊液中不易检出.Smith 和 Eickhoff 等认为脑脊液中免度球蛋白测定对鉴别化脓性脑膜炎、结核性脑膜炎和病毒性脑膜炎有一定价值。结核性脑膜炎 IgG 显著增高,病毒性脑膜炎时免疫球蛋白变化不大,化脓性脑膜炎的IgM 显著增高。本文50例流脑的脑脊液中 IgG、IgM显著增高(分别为21.12±9.18。4.71±2.39mg%;以正常人为对照组,分别为9±53.0;差异非
Normal cerebrospinal fluid IgG can be measured. Although the IgA content is very small, it can be detected at present. IgM is a macroglobulin with a large molecular weight of 900,000, which is difficult for normal people to penetrate due to the blood-brain barrier and therefore difficult to detect in cerebrospinal fluid. Smith and Eickhoff et al. Identification of purulent meningitis, tuberculous meningitis and viral meningitis have some value. Tuberculous meningitis was significantly higher IgG, viral meningitis immunoglobulin little change, purulent meningitis IgM was significantly higher. In this paper, cerebrospinal fluid of 50 cases of cerebrospinal fluid IgG, IgM was significantly higher (respectively 21.12 ± 9.18.4.71 ± 2.39mg%; normal human control group, respectively, 9 ± 53.0; difference