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目的探讨可逆性大脑后部脑病综合征(RPES)的病因、临床表现、影像学特征、鉴别诊断及治疗、预后。方法收集4例RPES患者的临床资料,分析其临床表现、影像学特征及治疗、预后,并复习文献。结果3例为子痫患者,1例为尿毒症患者,临床以突发头痛、视物不清、抽搐发作、意识障碍为特点;颅脑MRI、CT检查示大脑后部双侧顶枕叶皮质下白质多发病灶。行降颅压、脱水、抗惊厥治疗,临床症状及影像学表现均很快好转。结论RPES临床表现无特异性,经及时对症治疗后病情很快好转。
Objective To investigate the etiology, clinical manifestations, imaging features, differential diagnosis, treatment and prognosis of reversible posterior cerebral encephalopathy syndrome (RPES). Methods The clinical data of 4 patients with RPES were collected and analyzed for their clinical manifestations, imaging features, treatment, prognosis and review of the literature. Results Three patients were eclampsia and one was uremia. The patients were characterized by sudden headache, blurred vision, convulsive seizures and disturbance of consciousness. Brain MRI and CT examination showed that the occipital cortex Lower white matter multiple lesions. Line descending intracranial pressure, dehydration, anticonvulsant treatment, clinical symptoms and imaging findings are quickly improved. Conclusion The clinical manifestations of RPES are nonspecific, and their condition improves quickly after timely symptomatic treatment.