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目的探讨浙江省台州市人类免疫缺陷病毒(HIV)感染者中乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)及EB病毒(EBV)合并感染率,并分析其影响因素。方法对台州市所有可定期随访的167例HIV感染者进行流行病学调查,其中男性113例,女性54例;平均年龄40岁。采用ELISA方法检测确定其HBV、HCV和EBV的血清阳性率。利用单因素logistic回归模型分析数据。结果研究经异性性接触感染HIV 115例(68.9%)。HBV、HCV、EBV的感染率分别为7.2%、21.0%和93.4%;有2例HIV感染者同时感染了HBV、HCV、EBV等3种病毒;有35例(21.0%)HIV感染者同时感染了HCV和EBV。单因素logistic回归分析显示:HIV感染者中,农民的HBV感染率高于从事商业服务者,经血液途径感染HIV者的HCV感染率高于经性途径感染HIV者,已婚者的EBV感染率高于未婚者。结论当地HIV感染者中存在一定比例的HBV、HCV和EBV共感染者,不同特征的HIV感染者中HBV、HCV和EBV的共感染率不同。
Objective To investigate the co-infection rates of hepatitis B virus (HBV), hepatitis C virus (HCV) and Epstein-Barr virus (EBV) in human immunodeficiency virus (HIV) infected patients in Taizhou City, Zhejiang Province and analyze the influencing factors. Methods A total of 167 HIV-infected persons with regular follow-up in Taizhou City were investigated by epidemiological survey, including 113 males and 54 females with a mean age of 40 years. ELISA method was used to determine the seroprevalence of HBV, HCV and EBV. Data were analyzed using a one-factor logistic regression model. Results The study investigated 115 cases of HIV infection (68.9%) by heterosexual exposure. The infection rates of HBV, HCV and EBV were 7.2%, 21.0% and 93.4% respectively. Two cases of HIV infection were infected with three kinds of viruses including HBV, HCV and EBV at the same time. 35 cases (21.0% HCV and EBV. Univariate logistic regression analysis showed that the prevalence of HBV infection among peasants was higher among peasants than those engaged in commercial services, and the HCV infection rate among those infected with HIV was higher than those infected with HIV through sexual route. The EBV infection rate among married persons Higher than unmarried. Conclusion There is a certain proportion of co-infected patients with HBV, HCV and EBV among local HIV infected persons. The co-infection rates of HBV, HCV and EBV among different HIV infected persons are different.