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目的:探讨新生儿低血糖脑损伤时的脑电图改变与临床预后的关系。方法:针对56例低血糖脑损伤新生儿实施脑电生理功能检测,分析脑电生理功能改变与临床预后的关系。结果:EEG、aEEG、EP正常者生存率均显著高于死亡率(χ2=17.514、20.452、25.419,P<0.05);EEG、aEEG、EP异常者生存率均显著低于死亡率(χ2=-11.901、-11.399、-6.772,P<0.05)。EEG、aEEG、EP轻度异常者生存率均显著高于中、重度异常者(P<0.05)。结论:低血糖脑损伤新生儿的脑电生理功能异常程度与临床预后密切相关。脑电生理功能测定能直观、准确地反映神经损伤状态,利于临床预后早期评估。
Objective: To investigate the relationship between EEG changes and clinical prognosis in neonates with hypoglycemic brain injury. Methods: Fifty-six neonates with hypoglycemic brain injury were enrolled in this study. EEG electrophysiological tests were performed to analyze the relationship between the changes of electrophysiological function and clinical prognosis. Results: The survival rates of EEG, aEEG and EP were significantly higher than those of normal controls (χ2 = 17.514, 20.452, 25.419, P <0.05). The survival rates of EEG, aEEG and EP were significantly lower than those of normal controls (χ2 = 11.901, -11.399, -6.772, P <0.05). The survival rates of EEG, aEEG and EP with mild abnormalities were significantly higher than those with moderate and severe abnormalities (P <0.05). Conclusion: The degree of EEG dysfunction in neonates with hypoglycemic brain injury is closely related to clinical prognosis. EEG physiological function can intuitively and accurately reflect the status of nerve injury, which will benefit the early assessment of clinical prognosis.