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目的分析老年慢性阻塞性肺疾病患者肺部感染病原菌耐药性,为临床医生治疗慢性阻塞性肺疾病提供可靠依据。方法选择2014年1月—2015年2月治疗慢性阻塞性肺疾病继发肺部感染病的老年患者314例,收集患者晨痰送检验科检查,药物敏感性采用K-B法检测。结果检出细菌中以革兰阴性杆菌检出率最高,其次为革兰阳性球菌,革兰阴性杆菌中铜绿假单胞菌对氨苄西林/舒巴坦耐药率较高,鲍氏不动杆菌对头孢噻肟耐药率较高。结论老年慢性阻塞性肺疾病患者肺部感染的病原菌以多药耐药菌为主,并且以革兰阴性菌较多,临床医生应该选用对病原菌敏感性较高的抗菌药物治疗,合理使用抗菌药,提高治疗效果。
Objective To analyze the drug resistance of pulmonary pathogens in elderly patients with chronic obstructive pulmonary disease and provide a reliable basis for clinicians to treat chronic obstructive pulmonary disease. Methods From January 2014 to February 2015, 314 elderly patients with pulmonary infection secondary to chronic obstructive pulmonary disease (COPD) were selected. Patients were collected for sputum aspiration examination and drug susceptibility testing by K-B method. Results The highest detection rate of Gram-negative bacilli was found in the bacteria, followed by Gram-positive cocci. The rates of resistance to ampicillin / sulbactam of Pseudomonas aeruginosa in Gram-negative bacilli were higher. Acinetobacter baumannii Cefotaxime resistance rate higher. Conclusion The pathogens of pulmonary infection in elderly patients with chronic obstructive pulmonary disease are mainly multi-drug resistant bacteria, and more gram-negative bacteria, clinicians should choose antimicrobial agents with high sensitivity to pathogens, , Improve the treatment effect.