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目的:探讨甲氨蝶呤联合B超监视妇科手术仪在持续性异位妊娠治疗中的应用价值。方法:将60例持续性异位妊娠患者分成观察组和对照组各30例,观察组在B超监视妇科手术仪监视下经阴道宫旁注射甲氨蝶呤(MTX)50 mg,对照组予MTX75 mg肌肉注射。比较两组治疗后血β-人绒毛膜促性腺激素(β-HCG)下降百分比及不良反应的发生率。结果:观察组的血β-HCG下降百分比和不良反应发生率均明显优于对照组(P<0.05)。结论:在B超监视妇科手术仪监视下经阴道宫旁注射MTX50 mg对持续性异位妊娠治疗较MTX75mg肌肉注射更安全有效。
Objective: To investigate the value of methotrexate combined with B-monitoring gynecological surgical instrument in the treatment of persistent ectopic pregnancy. Methods: Sixty consecutive patients with persistent ectopic pregnancy were divided into observation group and control group with 30 cases each. The observation group received methotrexate (MTX) 50 mg under the surveillance of B-monitoring gynecological operation instrument, the control group MTX75 mg intramuscularly. The percentage of decline of β-HCG and the incidence of adverse reactions were compared between the two groups after treatment. Results: The percentage of β-HCG decreased and the incidence of adverse reactions in the observation group were significantly better than those in the control group (P <0.05). CONCLUSIONS: Transvaginal pyloric injection of MTX 50 mg under surveillance of a B-monitoring gynecological surgical instrument is more safe and effective than continuous intramuscular injection of MTX 75 mg in the treatment of persistent ectopic pregnancy.