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环核苷酸包括cAMP和cGMP。二者在组织和体液中的含量相对稳定并保持一定比例。如一方发生含量变化或比例改变,细胞功能也随之发生明显变化。我们应用中药制剂清胆注射液(以下简称清胆)治疗急性胆道感染有效率达89.7％,证明清胆对血浆环核苷酸的变化起着重要的作用。 选体重28～32g的健康小鼠32只,分为对照、清胆、内毒素和内毒素加清胆四组,每组8只,均为腹腔给药30分钟后取血样,测血浆环核苷酸含量,内毒素中毒组小鼠环核苷酸较对照组增加(P<0.05),以cAMP增
Cyclic nucleotides include cAMP and cGMP. The two in the organization and body fluid content is relatively stable and maintain a certain percentage. If a change occurs in the content or the proportion of changes in cell function also will be significant changes. Our application of traditional Chinese medicine Qingdan injection (hereinafter referred to as Qingdan) treatment of acute biliary tract infection rate of 89.7%, that clear gall on plasma cyclic nucleotide changes play an important role. Thirty-two healthy mice weighing 28-32g were divided into four groups: control, cholera, endotoxin, endotoxin plus choleretic, each group had 8 mice in each group, The content of nucleotide and the cyclic nucleotide of mice in endotoxin group were higher than that in control group (P <0.05)