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目的探讨由胃酸返流引起咳嗽的临床特点及质子泵抑制剂(PPI)联合胃动力药治疗的效果。方法对胃酸返流引起咳嗽的20例患者的临床表现进行分析及给予PPI和胃动力药治疗。结果 20例患者PPI和胃动力药治疗前曾误诊为变异型哮喘、慢性咽炎、肺炎、支气管炎等,专科治疗无效,而PPI和胃动力药治疗效果较好。结论对临床上因咳嗽伴反流或烧心就诊于各有关专科患者经相应的治疗无效或疗效欠佳时,应考虑存在胃食管反流病的可能,应及时行相应检查和治疗。
Objective To investigate the clinical characteristics of cough caused by acid reflux and the effect of proton pump inhibitor (PPI) and gastric motility drug treatment. Methods The clinical manifestations of 20 patients with gastric acid reflux caused by cough were analyzed and treated with PPI and gastric motility drug. Results Twenty patients were misdiagnosed as variant asthma, chronic pharyngitis, pneumonia and bronchitis before treatment of PPI and gastric motility drug. The specialist treatment was ineffective, while the PPI and gastric motility drug treatment was better. Conclusion Clinic patients with reflux due to cough or heartburn in the relevant specialist patients treated by the corresponding treatment ineffective or poor efficacy, the possibility of gastroesophageal reflux disease should be considered may be timely and appropriate inspection and treatment.