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目的:探讨肿瘤内科阿片类镇痛药物的应用情况,为临床合理用药提供依据。方法:研究对象为2010年1月~2012年1月在浙江省湖州市中心医院肿瘤科的698例住院患者,采用WHO推荐的限定日剂量法进行药物使用强度的计算,对本组患者住院期间阿片类镇痛药物的使用强度进行统计分析。结果:共有247例应用阿片类镇痛药物,占35.4%,应用强度为1.02。其中应用药物共11种,药物利用指数在1以上的6种,其余5种药物利用指数均<1。结论:《成人癌痛临床实践指南(中国版)》为肿瘤患者应用镇痛药物提供了标准,但由于个体差异,药物应用方面仍存在一定的不稳定性,临床应用方面应当参照要求,保证合理用药。
Objective: To investigate the application of opioid analgesics in oncology and provide the basis for clinical rational drug use. Methods: From January 2010 to January 2012 in Huzhou City Central Hospital of Zhejiang Province, Department of Oncology, 698 cases of inpatients, using the WHO recommended limit daily dose method for calculating the intensity of drug use, the patients in the hospital during the opium Analgesic analgesics were used for statistical analysis. RESULTS: A total of 247 opioid analgesics were used, accounting for 35.4% of the total, with a strength of 1.02. Among them, 11 kinds of drugs were used, 6 kinds of drug utilization indexes were above 1, and the remaining 5 kinds of drug utilization indexes were all <1. Conclusion: The Guidelines for Clinical Practice of Adult Cancer Pain (China Edition) provide a standard for the application of analgesics in cancer patients. However, due to individual differences, there are still some instabilities in the application of drugs. Clinical application should be based on the requirements to ensure reasonable Medication.