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用不同浓度孕酮(P)处理人精子,研究孕酮对人精子穿透去透明带金黄地鼠卵能力的影响。结果发现低浓度孕酮(20μmol/L)使人精子的穿卵率和穿卵指数均有极显著的提高,而高浓度孕酮(1000μmol/L)则对人精子穿卵率和穿卵指数有降低作用。提示人工授精时可用低浓度孕酮处理穿卵率低下的病人精子,以提高人工授精的成功率
The effects of progesterone on the ability of human sperm to penetrate into the zona pellucida of golden hamster were studied by treating human sperm with different concentrations of progesterone (P). The results showed that low concentration of progesterone (20μmol / L) significantly increased the rate of penetration of human sperm and the index of ovulation, while the high concentration of progesterone (1000μmol / L) Have a lower role. Tip artificial insemination can be used when the low concentration of progesterone in treatment of low sperm penetration rate of patients to improve the success rate of artificial insemination