本文目的在于估价LTs在介导人的生理或病理生理过程中的潜在作用.尽管LTs的生理意义因受分析技术的限制有待进一步研究,但本文综合的资料强烈提示LTs可能在过敏反应、哮喘、休克、组织损伤以及炎症反应中起重要作用.在这些病理改变中(主要来自实验动物)已检出LTs,而且LT拮抗剂或合成抑制剂可改善某些疾病过程. The purpose of this article is to evaluate the potential role of LTs in mediating physiological or pathophysiological processes in humans.Although the physiological significance of LTs remains to be further studied by analytical techniques, the data presented here strongly suggest that LTs may play a role in allergic reactions, asthma, Shock, tissue damage and inflammatory response, LTs have been detected in these pathological changes (mainly from experimental animals), and LT antagonists or synthetic inhibitors may improve certain disease processes.