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作者治疗小儿牙源性颌骨骨髓炎143例,年龄3～14岁。上颌骨髓炎43例(急性38例,慢性5例),下颌骨髓炎100例(急性69例,慢性31例)。综合治疗分为用和不用左旋咪唑两组,左旋咪唑剂量每公斤体重2.5mg,每周2次睡前服,共1～3周。在患儿入院时、治疗7～15天时,有的经过1～6月以后进行免疫学检查,包括T和B淋巴细胞含量、PHA淋巴细胞转化试验、白细胞移动抑制试验、血清免疫球蛋白浓度。研究结果患儿入院时,T细胞百分数降低,急性骨髓炎降低到44.38±1.76％(正常52.34±1.59％),慢性骨髓炎降低到41.12±2.25％。淋巴细胞增生活性明显降低,淋巴细
The authors treat pediatric odontogenic osteomyelitis in 143 cases, aged 3 to 14 years. 43 cases of maxillary osteomyelitis (acute 38 cases, chronic 5 cases), mandibular osteomyelitis 100 cases (69 cases of acute, chronic 31 cases). Comprehensive treatment is divided into two groups with and without levamisole, levamisole 2.5mg per kilogram of body weight, 2 times a week before going to bed, a total of 1 to 3 weeks. In children with admission, the treatment of 7 to 15 days, and some after 1 to 6 months after immunological examination, including T and B lymphocyte content, PHA lymphocyte transformation test, leukocyte migration inhibition test, serum immunoglobulin concentration. Results At admission, the percentage of T-cells decreased, acute osteomyelitis decreased to 44.38 ± 1.76% (normal 52.34 ± 1.59%), and chronic osteomyelitis decreased to 41.12 ± 2.25%. Lymphocyte proliferation decreased significantly, lymphocytes