目的：探讨腹腔镜联合内镜治疗胃间质瘤的临床疗效，分析其可行性及临床应用价值。方法对20例胃间质瘤患者采用腹腔镜联合内镜进行微创手术。结果20例患者均顺利完成手术，无中转开腹，手术时间50～120 min（平均85 min），术后无吻合口出血、梗阻、吻合口瘘等并发症，均顺利出院。结论腹腔镜技术能弥补内镜和影像学检查的不足，与内镜联合治疗胃间质瘤定位准确，创伤小，恢复快，安全可行，临床应用前景广阔。“,”Objective To evaluate the effects,feasibility and clinical values of combined laparoscopic and endoscopic treatment for the diagnosis and treatment of gastric stromal tumors.Methods Twenty patients with gastric stromal tumors received laparoscopy and endoscopy for minimally invasive surgery.Results All surgeries were successfully completed without laparotomy conversion.The operativetime ranged from 50 to 120 minutes,with an average 85 minutes.No case had anastomotic bleeding,obstruction or anastomotic leak and they all discharged uneventfully.Conclusion Laparoscopy can make upfor the shortcomings of endoscopy and imaging examination.Combined laparoscopic and endoscopic treatment has the advantages of precise positioning,small truma,quick recovery,safety and feasibility,whichexists broad prospects for clinical application.