用Hela细胞培养法调查224例用抗生素治疗及86例未用抗生素者粪中艰难梭状芽胞杆菌毒素B检出率、毒素效价及捡出率与抗生素种类的关系。结果表明多种抗生素组的检出率高于单一抗生素组,但毒素B的存在、效价与腹泻的关系,敏感性和特异性均不高,仅能配合临床资料作辅助诊断。 Using Hela cell culture method to investigate 224 cases of antibiotic treatment and 86 cases without antibiotics, the detection rate of Clostridium difficile toxins B, toxin potency and the detection rate of the relationship with the type of antibiotics. The results showed that the detection rate of multiple antibiotics group was higher than single antibiotic group, but the presence of toxin B, the relationship between potency and diarrhea, sensitivity and specificity are not high, only with the clinical data for diagnosis.