This paper deals with observer design for generalized Hamiltonian systems and its applications. First, by using the systems’ structural properties, a new observer design method called Augment Plus Feedback is provided and two kinds of observers are obtained: non-adaptive and adaptive ones. Then, based on the obtained observer, H∞ control design is investigated for generalized Hamiltonian systems, and an observer-based control design is proposed. Finally, as an application to power systems, an observer and an observer-based H∞ control law are designed for single-machine infinite-bus systems. Simulations show that both the observer and controller obtained in this paper work very well. This paper deals with observer design for generalized Hamiltonian systems and its applications. First, by using the systems’ structural properties, a new observer design method called Augment Plus Feedback is provided and two kinds of observers are obtained: non-adaptive and adaptive ones. Then, based on the obtained observer, H∞ control design is investigated for investigated in generalized Hamiltonian systems, and an observer-based control design is proposed. Finally, as an application to power systems, an observer and an observer-based H∞ control law are designed for single-machine infinite-bus systems. Simulations show that both the observer and controller obtained in this paper work very well.