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目的分析急性炎症因子C反应蛋白在深静脉血栓合并肺栓塞患者中的临床价值。方法对西安交通大学医学院第一附属医院2009年3月-2010年3月之间收住院的经过顺行性静脉造影或下肢静脉超声临床确诊的静脉血栓栓塞症患者268例进行统计,分为单纯深静脉血栓组(198例)和深静脉血栓合并肺栓塞组(70例),常规测定血浆C反应蛋白含量,分析两组C反应蛋白有无统计学差异。结果应用SPSS 13.0软件进行统计分析,并进行独立样本的t检验,结果表明深静脉血栓合并肺栓塞组C反应蛋白(72.780±33.724)mg/L明显高于单纯深静脉血栓组(39.220±49.633)mg/L,P<0.05。结论 C反应蛋白显著异常患者肺栓塞的可能性较大,C反应蛋白可以作为深静脉血栓住院患者合并肺栓塞的预测因子。
Objective To analyze the clinical value of acute inflammatory cytokine C-reactive protein in patients with deep venous thrombosis complicated with pulmonary embolism. Methods A total of 268 patients with venous thromboembolism who underwent routine venography or venous ultrasonography in the First Affiliated Hospital of Xi’an Jiaotong University School of Medicine from March 2009 to March 2010 were analyzed and divided into Simple deep venous thrombosis group (198 cases) and deep venous thrombosis with pulmonary embolism group (70 cases), routine determination of plasma C-reactive protein content, analysis of two groups of C-reactive protein was statistically significant. Results SPSS 13.0 software was used for statistical analysis and independent sample t test. The results showed that C reactive protein (72.780 ± 33.724) mg / L in deep venous thrombosis complicated with pulmonary embolism was significantly higher than that in simple deep vein thrombosis (39.220 ± 49.633) mg / L, P <0.05. Conclusions Patients with significant abnormalities in C-reactive protein are more likely to have pulmonary embolism. C-reactive protein may be used as a predictor of pulmonary embolism in hospitalized patients with deep venous thrombosis.