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为了评价腹腔化疗对进展期胃肠癌根治术后腹腔内复发和肝转移的预防价值,我院对1996-02/1998-02经手术及病理证实的98例进展期胃肠道癌患者进行了腹腔化疗和静脉化疗的对比研究,现报告如下。 1 材料和方法 1.1 材料 将1996-02/1998-02接受根治性切除手术(D2)并经病理证实侵及浆膜或浆膜外的进展期胃肠癌98例作为研究对象,随机将其分为腹腔化疗组(50例)和静脉化疗组(48例)。腹腔化疗组平均年龄48岁,男32例,女18例,肿瘤位于胃处16例,大肠处34例,高分化腺癌34例,低分化腺癌10例,粘液腺癌11例,胃癌按国际分期16例均为Ⅲ期,大肠癌按Dukes’分期34例均为D期。静脉化疗组平均年龄51岁,男33例,女15例,肿瘤位于胃处14例,大肠处34例,高分化腺癌31例,低分化腺癌9例,粘液腺癌8例,胃癌按国际分期14例,大肠癌按
To evaluate the prevention value of intraperitoneal chemotherapy for intraperitoneal recurrence and hepatic metastasis after radical gastrointestinal cancer surgery, our hospital performed 96 cases of advanced gastrointestinal cancer confirmed by surgery and pathology from 1996-02/1998-02. A comparative study of intraperitoneal chemotherapy and intravenous chemotherapy is reported below. 1 Materials and Methods 1.1 Materials Randomized subtotals of 98 cases of advanced gastrointestinal cancer outside the serosal or serosal membrane during the radical resection (D2) from 1996-02/1998-02 were studied. For the intraperitoneal chemotherapy group (50 cases) and intravenous chemotherapy group (48 cases). The average age of the intraperitoneal chemotherapy group was 48 years old, 32 males and 18 females. The tumors were located in the stomach at 16 cases, the large intestine at 34 cases, well-differentiated adenocarcinoma in 34 cases, poorly differentiated adenocarcinoma in 10 cases, and mucinous adenocarcinoma in 11 cases. In the international phase, all 16 cases were in stage III, and 34 cases of colorectal cancer were all D stages according to the Dukes’ stage. The average age of the intravenous chemotherapy group was 51 years, 33 males and 15 females. The tumor was located in the stomach at 14 cases, the large intestine at 34 cases, well-differentiated adenocarcinoma in 31 cases, poorly differentiated adenocarcinoma in 9 cases, and mucinous adenocarcinoma in 8 cases. International stage 14 cases, colorectal cancer