目的:优选九味蒲芍胶囊处方中挥发油的最佳提取工艺。方法:采用水蒸气蒸馏法提取挥发油,以挥发油提取量为指标,选择药材粉碎度、加水倍数、提取时间为因素,采用正交实验设计优化提取工艺。结果:挥发油的最佳提取工艺为药材粗碎过24目筛,加8倍量水,提取8h。结论:优化的提取工艺稳定可靠,可用于九味蒲芍胶囊处方中含挥发油中药材的提取。 Objective: To optimize the extraction process of volatile oil in prescription of Jiuwei Pushao capsule. Methods: Volatile oil was extracted by steam distillation. The extraction yield of volatile oil was used as an index. The degree of pulverization, the times of water addition and extraction time were selected as the indexes. The orthogonal design was used to optimize the extraction process. Results: The best extraction of volatile oil herbs for the first 24 mesh sieve, add 8 times the amount of water, extracted 8h. Conclusion: The optimized extraction process is stable and reliable and can be used for extraction of Chinese herbal medicines containing volatile oil in the prescription of Jiuwei Pushao capsule.